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Ionis Pharma To Present Detailed Data From Pivotal Phase 3 CORE And CORE2 Studies Of Olezarsen In People With sHTG At AHA Scientific Sessions In New Orleans

Author: Benzinga Newsdesk | October 27, 2025 07:13am

– Ionis to host webcast on Saturday, November 8 at 3:00 p.m. ET to discuss results –

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) today announced that detailed data from the landmark pivotal Phase 3 CORE and CORE2 studies of olezarsen in people with severe hypertriglyceridemia (sHTG) will be presented during a late-breaking session, titled "Groundbreaking Trials in Cardiometabolic Therapeutics", at the American Heart Association (AHA) Scientific Sessions in New Orleans.

Ionis previously reported positive topline results from the Phase 3 CORE and CORE2 studies, in which olezarsen demonstrated a highly statistically significant reduction in fasting triglycerides and acute pancreatitis events with favorable safety and tolerability. Ionis plans to submit a supplemental new drug application to the U.S. Food and Drug Administration by the end of the year.

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