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Revolution Medicines, Disc Medicine, American Express And Other Big Stocks Moving Higher On Friday

Author: Avi Kapoor | October 17, 2025 12:02pm

U.S. stocks were mostly higher, with the Dow Jones index gaining more than 150 points on Friday.

Shares of Revolution Medicines Inc (NASDAQ:RVMD) rose sharply during Friday's session after the company announced that the FDA granted the company a non-transferrable voucher for daraxonrasib, the company’s RAS(ON) multi-selective inhibitor, under the Commissioner’s National Priority Voucher pilot program.

Revolution Medicines shares jumped 11.2% to $55.25 on Friday.

Here are some other big stocks recording gains in today’s session.

  • Disc Medicine Inc (NASDAQ:IRON) shares gained 25.7% to $93.50 after the company announced that it received a Commissioner’s National Priority Voucher from the FDA for bitopertin in erythropoietic protoporphyria, including X-linked protoporphyria. Wedbush maintained an Outperform rating on the stock and raised its price target from $90 to $110.
  • Liberty Energy Inc (NYSE:LBRT) gained 23.4% to $14.73 following third-quarter results.
  • Solana Co (NASDAQ:HSDT) gained 19.5% to $12.08.
  • Sealsq Corp (NASDAQ:LAES) surged 14.4% to $7.28.
  • Rekor Systems Inc (NASDAQ:REKR) gained 13.3% to $2.94.
  • Praxis Precision Medicines Inc (NASDAQ:PRAX) gained 12.5% to $183.00 as the company announced pricing of $525 million public offering.
  • Sify Technologies Ltd (NYSE:SIFY) gained 11.8% to $13.15.
  • Kenvue Inc (NYSE:KVUE) gained 8.4% to $15.30.
  • Propetro Holding Corp (NYSE:PUMP) surged 7.6% to $5.52.
  • Owens & Minor Inc (NYSE:OMI) gained 6.7% to $4.90.
  • American Express Co (NYSE:AXP) surged 6% to $342.57 as the company reported third-quarter 2025 results on Friday, surpassing analyst estimates for both revenue and adjusted earnings per share.
  • AppFolio Inc (NASDAQ:APPF) gained 4.7% to $233.90. Keybanc analyst Jason Celino upgraded AppFolio from Sector Weight to Overweight and announced a $285 price target.

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Posted In: APPF AXP HSDT IRON KVUE LAES LBRT OMI PRAX PUMP REKR RVMD SIFY

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