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News

Insmed Presents Patient-Reported Outcomes And Microbiologic Data from Phase 3 ARISE Study Of ARIKAYCE In Patients With NTM Lung Disease Caused By MAC At American Thoracic Society 2024 International Conference Plenary Session

Author: Benzinga Newsdesk | May 20, 2024 04:29pm

—Patients Treated with ARIKAYCE Plus Macrolide-Based Background Regimen Had Meaningfully Greater Improvements in Respiratory Symptoms vs. Macrolide-Based Background Regimen Alone, As Measured By the QOL-B Respiratory Domain Instrument—

—QOL-B Respiratory Domain Scores for ARIKAYCE Patients Showed Improvement Through Month 6 and Continued to Improve Through Month 7 (1 Month Off Treatment), While Improvements in the Comparator Arm Plateaued After Month 3 and Worsened After Month 6—

—Microbiologic Data Presented Showed Patients in the ARIKAYCE-treated Arm Had Numerically Greater Rates of Culture Conversion By Month 6, and Nominally Statistically Significantly Higher Rates By Month 7, With Earlier Time to First Culture Conversion vs. Comparator Arm—

—No Study Patients Developed MAC with Resistance to ARIKAYCE or Macrolides—

Posted In: INSM