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Korro Presents Additional Preclinical Data For KRRO-110 At American Thoracic Society 2024 International Conference

Author: Benzinga Newsdesk | May 20, 2024 02:33pm
  • KRRO-110 showed sustained editing efficiency of approximately 60% and increased total alpha-1 antitrypsin (AAT) protein levels to greater than 60uM at week 13 in an in vivo genetic Alpha-1 Antitrypsin Deficiency (AATD) mouse model

     
  • KRRO-110 showed 35µM of M-AAT one week post the first dose, with 0µM of M-AAT at baseline, increasing to 45µM of M-AAT at week 13

Posted In: KRRO


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