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Editas Medicine To Present Pre-Clinical Data Demonstrating Progression Of In Vivo Medicines Pipeline At American Society Of Gene And Cell Therapy Annual Meeting

Author: Benzinga Newsdesk | April 22, 2024 04:33pm

Editas Medicine presentations at ASGCT include:

  • Oral presentation of in vivo pre-clinical data from mouse studies using lipid nanoparticle (LNP)-mediated delivery of an optimized guide RNA (gRNA) and engineered AsCas12a messenger RNA (mRNA).
  • Pre-clinical data demonstrating AsCas12a gRNA modifications that enable high-potency gene editing in multiple cell types and improve gene editing outcomes in vivo, enabling the development of in vivo gene editing medicines.
    • Research on identifying potent large serine recombinases (LSRs) as a foundation to develop novel in vivo gene editing technologies for whole gene knock-in, expanding potential in vivo gene editing targets for developing medicines.
       

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