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Vigil Neuroscience, Inc. (NASDAQ:VIGL), a clinical-stage biotechnology company committed to harnessing the power of microglia for the treatment of neurodegenerative diseases, today presented preclinical data on the profile of VG-3927 in an oral presentation at the AD/PD™ 2024 International Conference on Alzheimer's and Parkinson's Diseases being held March 5 – March 9 in Lisbon Portugal.
The presentation outlines preclinical data on the agonist pharmacology of VG-3927, its effect on AD-associated neuropathological endpoints, and its potential as a disease-modifying therapeutic for the treatment of AD.
"As the first and only small molecule TREM2 agonist to enter clinical development, we are thrilled to have an opportunity to further demonstrate the differentiated profile for VG-3927 and how it could represent a significant treatment advancement for those living with AD," said David Gray, PhD, Chief Science Officer at Vigil. "Having recently commenced dosing in our Phase 1 healthy volunteer clinical trial evaluating VG-3927, we look forward to further investigating this mechanism of action and its potential as a disease-modifying therapeutic."
Presentation Details:
Title: Characterization of the First Small Molecule TREM2 Agonist, VG-3927, for Clinical Development in Alzheimer's Disease
Presenter: Christian Mirescu, PhD, Vice President, Head of Neuroimmunology, Vigil Neuroscience, Inc.
Presentation Session: 2780 - MICROGLIA. TREM1, TREM2, MICROGLIA, NEUROINFLAMMATION (ID 24)
Date and Time: March 6th 2:30pm (Local Time) / 9:30am (ET)
Posted In: VIGL
