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AdventHealth, Mass General Brigham, Mayo Clinic, MUSC, and UPMC will leverage Quanterix technology and assays to streamline care for Alzheimer's patients
Quanterix Corporation (NASDAQ:QTRX), a leading provider of ultra-sensitive research products and high-definition diagnostics, today announced its first collaborations with health systems in pursuit of their shared goal to improve and simplify Alzheimer's disease (AD) diagnosis. These relationships further the company's goal to build the global infrastructure necessary for AD testing by expanding clinical access to Quanterix's leading blood biomarker assays.
Collectively AdventHealth, Mass General Brigham, Mayo Clinic, South Carolina Alzheimer's Disease Research Center (SC-ADRC) at the Medical University of South Carolina, and UPMC represent 140+ hospitals across 18 states, caring for approximately 21 million patients in their hospital networks. This reach will provide greater access to patients for high-accuracy, non-invasive AD testing. Quanterix can enable health systems to access Alzheimer's blood biomarker tests through a variety of models, including sample processing through Lucent Diagnostics, Quanterix's diagnostic testing brand, or by installing Simoa technology in-house to develop and validate their own Laboratory Developed Tests (LDTs).
Blood-based biomarker testing offers Alzheimer's patients a non-invasive method and greater access to AD testing overall. Traditional AD diagnosis has relied on combination of symptom presentation, brain imaging, and the detection of CSF biomarkers for AD. This approach is not only burdensome and invasive for patients, but also costly, making them unsuitable for most primary and secondary care settings1. This inaccessibility has left 50-70% of symptomatic AD patients without a correct and timely diagnosis, impacting quality of life, medical autonomy, and general wellbeing1. With 15 million Americans predicted to be affected by Alzheimer's by 2060,2 high-accuracy, easily accessible blood testing will play a critical role in early detection and treatment of Alzheimer's. Quanterix's Simoa p-Tau 217 assays provide high accuracy, consistent with the recommendations in the recent NIA-AA criteria for Alzheimer's diagnosis3, stating that p-Tau 217 is the only plasma biomarker appropriate for Alzheimer's diagnosis.
"New resources available to aid in diagnosis and treatment of Alzheimer's disease have contributed to a more optimistic environment for AD patient care," said Kirk Erickson, PhD, director of translational neuroscience at the AdventHealth Neuroscience Institute. "With simplified, affordable, non-invasive testing methods, physicians can proactively evaluate and monitor patients with memory concerns. The availability of blood-based biomarker testing to the AdventHealth network has the potential to help a wide population concerned about mild cognitive impairment and aid physicians in their diagnosis."
"As we see how well blood measures of p-Tau 217 perform," said Dr. Brad Dickerson, MD of Mass General Neurology and Harvard Medical School, "it is exciting to plan for this new tool in our workflow to make an early, accurate diagnosis if a patient is suspected of having Alzheimer's disease."
"In our pursuit to build the global testing infrastructure for Alzheimer's disease, Quanterix is pleased to work with several health systems whose combined networks treat millions of patients," said Masoud Toloue, CEO of Quanterix. "There is a critical need for easily accessible, time- and cost-effective diagnostic tools for Alzheimer's. By working with these leading hospitals, we are taking an important step just as disease modifying therapies become available to patients suffering from this disease.
Quanterix's commitment to establishing the industry standard for accuracy continues to position the company as a critical partner for AD testing. Beyond these five health systems, Quanterix is initiating partnerships with reference laboratories and hospitals globally to enable patients with cognitive symptoms consistent with Alzheimer's disease to be tested.
For more information about Quanterix's work in neurology, visit: https://www.quanterix.com/therapeutic-areas/neurology/.
Posted In: QTRX
