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Anixa Biosciences, Inc. ("Anixa" or the "Company") (NASDAQ:ANIX), a biotechnology company focused on the treatment and prevention of cancer, today announced that Dr. Pamela D. Garzone, Anixa's Chief Development Officer, has been invited to present at the 8th Annual CAR-TCR Summit being held from August 29 – September 1, 2023 in Boston, MA.
The 8th Annual CAR-TCR Summit is the world's pre-eminent industry-leading comprehensive forum that unites the global cell therapy community across a variety of cell types. During this three-day event over one thousand attendees from over three hundred companies will come together to explore discovery through commercialization to deliver safe, effective and commercially viable CAR and TCR therapies.
Entitled "Developing a CAR-T for Ovarian Cancer and Other Solid Tumors," the presentation will focus on the opportunities and challenges of CAR-T for solid tumors, routes of administration besides intravenous infusions and details of the ovarian cancer CAR-T therapy clinical trial (NCT05316129) under the direction of Dr. Robert Wenham at Moffitt Cancer Center and in collaboration with Anixa. This trial, a Phase I clinical trial of autologous T cells genetically engineered with a chimeric receptor to target the follicle-stimulating hormone receptor (FSHR) in patients with recurrent ovarian cancer, will evaluate intraperitoneal and intravenous administration of the CAR-T and the role of lymphodepletion. The study commenced July of 2022 and is in progress.
Dr. Garzone will also be hosting a roundtable discussion titled, "Impacting CAR-T Efficacy with Pre-Conditioning Regimens." Topics covered during this roundtable will include discussion on differences between lymphodepletion regimens and outcomes for liquid and solid tumors, impact of lymphodeletion intensity on CAR-T cell therapy, and how to achive optimal balance between efficacy and safety.
Posted In: ANIX
